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Article

Structure and evolution of a group of related aminoacyl-tRNA synthetases.

Journal of molecular biology - 5 Apr 1991

Gatti D L, Tzagoloff A

Abstract excerpt

A yeast nuclear gene, designated MSK1, has been selected from a yeast genomic library by transformation of a respiratory deficient mutant impaired in acylation of mitochondrial lysine tRNA. This gene confers a respiratory competent phenotype and restores the mutant's ability to acylate the mitochondrial lysine tRNA. The amino acid sequence of the protein encoded by MSK1 is homologous to yeast cytoplasmic...

Topics

Adenosine Triphosphate
Amino Acid Sequence
Aspartate-tRNA Ligase
Biological Evolution
Blotting, Southern
Blotting, Western
Cloning, Molecular
Escherichia coli
Genes, Fungal
Genotype
Lysine-tRNA Ligase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Mutation

Restriction Mapping

Saccharomyces cerevisiae

Sequence Homology, Nucleic Acid

Source

Identifiers

PMID: 2016746
DOI: 10.1016/0022-2836(91)90701-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2016746-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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