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Article

Molecular characterisation of a recurrent, semi-cryptic RUNX1 translocation t(7;21) in myelodysplastic syndrome and acute myeloid leukaemia.

British journal of haematology - 1 Mar 2010

Foster Nicola, Paulsson Kajsa, Sales Mark, Cunningham Joan, Groves Michael, O'Connor Nigel, Begum Suriya, Stubbs Tracy, McMullan Dominic J, Griffiths Michael, Pratt Norman, Tauro Sudhir

Abstract excerpt

A proportion of cytogenetic abnormalities in myelodysplastic syndromes (MDS) and acute myeloid leukaemia (AML) may escape detection by high-resolution genomic technologies, but can be identified by conventional cytogenetic and molecular analysis. Here, we report the detection of a reciprocal tran...

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Topics

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Share to Chromosomes, Human, Pair 21
Share to Chromosomes, Human, Pair 7

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Core Binding Factor Alpha 2 Subunit

Share to In Situ Hybridization, Fluorescence

Share to Leukemia, Myeloid, Acute

Share to Myelodysplastic Syndromes

Share to Neoplasm Proteins

Share to Translocation, Genetic

Source

Identifiers

PMID: 20064152
DOI: 10.1111/j.1365-2141.2009.08039.x

Genes

RUNX1
USP42

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20064152-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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