Article
Insights from genomic comparisons of genetically monomorphic bacterial pathogens.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 19 Mar 2012
Achtman Mark
Abstract excerpt
Some of the most deadly bacterial diseases, including leprosy, anthrax and plague, are caused by bacterial lineages with extremely low levels of genetic diversity, the so-called 'genetically monomorphic bacteria'. It has only become possible to analyse the population genetics of such bacteria since the recent advent of high-throughput comparative genomics. The genomes of genetically monomorphic lineages contain...
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