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Article

TGFbeta inducible early gene-1 directly binds to, and represses, the OPG promoter in osteoblasts.

Biochemical and biophysical research communications - 29 Jan 2010

Subramaniam M, Hawse J R, Bruinsma E S, Grygo S B, Cicek M, Oursler M J, Spelsberg T C

Abstract excerpt

TGFbeta inducible early gene-1 (TIEG) is a member of the Krüppel-like family of transcription factors (KLF10) that plays an important role in TGFbeta mediated Smad signaling. In order to better understand the role of TIEG in bone, we generated TIEG knockout (KO) mice. Calvarial osteoblasts (OBs)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20059964
DOI: 10.1016/j.bbrc.2009.12.171
PMCID: PMC2828289

Genes

KLF10

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20059964-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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