Prostate cancer risk allele specific for African descent associates with pathologic stage at prostatectomy.

doi:10.1158/1055-9965.EPI-08-1111

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Article

Prostate cancer risk allele specific for African descent associates with pathologic stage at prostatectomy.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jan 2010

Whitman Eric J, Pomerantz Mark, Chen Yongmei, Chamberlin Michael M, Furusato Bungo, Gao Chunling, Ali Amina, Ravindranath Lakshmi, Dobi Albert, Sesterhenn Isabell A, Sestrehenn Isabell A, McLeod David G, Srivastava Shiv, Freedman Matthew, Petrovics Gyorgy

Abstract excerpt

PURPOSE: A region on chromosome 8q24 was recently identified as a novel prostate cancer risk locus. Inherited variation in this region is associated with prostate cancer risk in the general population (21-58%), and specific alleles show a strong association in African-American men. This study was designed to evaluate associations between 8q24 risk alleles and clinical variables, such as pathologic stage, age at...

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Identifiers

PMID: 20056617
DOI: 10.1158/1055-9965.EPI-08-1111
PMCID: PMC6880746

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