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Studies on the genetic control of resistance of black hooded rats to Borna disease

1 Mar 1991

Abstract excerpt

In contrast to Lewis (LEW) and Wistar rats, black hooded (BH) rats inoculated with Borna disease (BD) virus developed neither encephalitis nor clinical disease despite persistent replication of the virus in the central nervous system. In comparison to LEW rats, production of virus-specific antibodies was significantly delayed in BD-resistant BH rats, even though identical titres were finally reached. The...

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PMID: 2005432
DOI: 10.1099/0022-1317-72-3-535

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