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Article

Leukemia-initiating cells from some acute myeloid leukemia patients with mutated nucleophosmin reside in the CD34(-) fraction.

Blood - 11 Mar 2010

Taussig David C, Vargaftig Jacques, Miraki-Moud Farideh, Griessinger Emmanuel, Sharrock Kirsty, Luke Tina, Lillington Debra, Oakervee Heather, Cavenagh Jamie, Agrawal Samir G, Lister T Andrew, Gribben John G, Bonnet Dominique

Abstract excerpt

Leukemia-initiating cells (LICs) in acute myeloid leukemia (AML) are believed to be restricted to the CD34(+) fraction. However, one of the most frequently mutated genes in AML is nucleophosmin (NPM), and this is associated with low CD34 expression. We, therefore, investigated whether NPM-mutated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20053758
DOI: 10.1182/blood-2009-02-206565
PMCID: PMC2837317

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20053758-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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