Article
Functional assessment of human dendritic cells labeled for in vivo (19)F magnetic resonance imaging cell tracking.
Cytotherapy - 1 Apr 2010
Helfer Brooke M, Balducci Anthony, Nelson Aaron D, Janjic Jelena M, Gil Roberto R, Kalinski Pawel, de Vries I Jolanda M, Ahrens Eric T, Mailliard Robbie B
Abstract excerpt
BACKGROUND AIMS: Dendritic cells (DC) are increasingly being used as cellular vaccines to treat cancer and infectious diseases. While there have been some promising results in early clinical trials using DC-based vaccines, the inability to visualize non-invasively the location, migration and fate of cells once adoptively transferred into patients is often cited as a limiting factor in the advancement of these...
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