Article
Magnetic resonance tracking of dendritic cells in melanoma patients for monitoring of cellular therapy.
Nature biotechnology - 1 Nov 2005
de Vries I Jolanda M, Lesterhuis W Joost, Barentsz Jelle O, Verdijk Pauline, van Krieken J Han, Boerman Otto C, Oyen Wim J G, Bonenkamp Johannes J, Boezeman Jan B, Adema Gosse J, Bulte Jeff W M, Scheenen Tom W J, Punt Cornelis J A, Heerschap Arend, Figdor Carl G
Abstract excerpt
The success of cellular therapies will depend in part on accurate delivery of cells to target organs. In dendritic cell therapy, in particular, delivery and subsequent migration of cells to regional lymph nodes is essential for effective stimulation of the immune system. We show here that in vivo magnetic resonance tracking of magnetically labeled cells is feasible in humans for detecting very low numbers of...
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