Article
KRAS mutation analysis on cytological specimens of metastatic colo-rectal cancer.
Diagnostic cytopathology - 1 Dec 2010
Troncone Giancarlo, Malapelle Umberto, Cozzolino Immacolata, Palombini Lucio
Abstract excerpt
Recent evidences showed that metastatic colorectal cancer (CRC) patients with tumors harboring a KRAS gene mutation do not derive benefit from the administration of epidermal growth factor receptor-directed monoclonal antibodies. Typically, the specimens available for KRAS mutational analysis are...
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