Article
Analysis of GSTM1 and GSTT1 polymorphisms in circulating plasma DNA of lung cancer patients.
Molecular and cellular biochemistry - 1 May 2010
Cabral Rosa Estela Caseira, Caldeira-de-Araujo Adriano, Cabral-Neto Januario Bispo, Costa Carvalho Maria da Gloria
Abstract excerpt
The concentration of free circulating plasma DNA and the genetic profile of patients suffering from various types of tumors were studied in an effort to increase the understanding of the biomarkers and genetic factors involved in predisposing an individual to lung cancer (LC). The polymorphic inheritance of glutathione S-transferases (GST), which modulate the effects of various genotoxic agents, especially those...
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