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Article

Slowing bacterial translation speed enhances eukaryotic protein folding efficiency.

Journal of molecular biology - 12 Mar 2010

Siller Efraín, DeZwaan Diane C, Anderson John F, Freeman Brian C, Barral José M

Abstract excerpt

The mechanisms for de novo protein folding differ significantly between bacteria and eukaryotes, as evidenced by the often observed poor yields of native eukaryotic proteins upon recombinant production in bacterial systems. Polypeptide synthesis rates are faster in bacteria than in eukaryotes, bu...

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Identifiers

PMID: 20043920
DOI: 10.1016/j.jmb.2009.12.042

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20043920-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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