Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effects of measured susceptibility genes on cancer risk in family studies.

Human genetics - 1 Mar 2010

Wu Chih-Chieh, Strong Louise C, Shete Sanjay

Abstract excerpt

Numerous family studies have been performed to assess the associations between cancer incidence and genetic and non-genetic risk factors and to quantitatively evaluate the cancer risk attributable to these factors. However, mathematical models that account for a measured hereditary susceptibility gene have not been fully explored in family studies. In this report, we proposed statistical approaches to precisely...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Family
Share to Genes, p53
Share to Germ-Line Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Infant

Share to Infant, Newborn

Share to Linkage Disequilibrium

Share to Models, Genetic

Share to Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 20039063
DOI: 10.1007/s00439-009-0774-y
PMCID: PMC2918266

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effects of measured susceptibility genes on cancer risk in family studies.PMID 20039063Read ↗

Risk of differential cancer types over age in families with Li-Fraumeni syndrome: a validation study using multi-center cohortsSemantic proximity Read ↗

Joint effects of germ-line p53 mutation and sex on cancer risk in Li-Fraumeni syndrome.Semantic proximity Read ↗

Joint effects of germ-line TP53 mutation, MDM2 SNP309, and gender on cancer risk in family studies of Li-Fraumeni syndrome.Semantic proximity Read ↗

The genetic epidemiology of cancer: interpreting family and twin studies and their implications for molecular genetic approaches.Semantic proximity Read ↗

Genetic predisposition to sporadic cancer: how to handle major effects of minor genes?Semantic proximity Read ↗

Risk of multiple primary cancer diagnosis over age in families of Li-Fraumeni syndrome: a single institution perspectiveSemantic proximity Read ↗

A comprehensive survey of cancer risks in extended families.Semantic proximity Read ↗

Penetrance of Different Cancer Types in Families with Li-Fraumeni Syndrome: A Validation Study Using Multicenter Cohorts.Semantic proximity Read ↗

Relationships between familial risks of cancer and the effects of heritable genes and their SNP variants.Semantic proximity Read ↗

Estimating disease risks for individuals with a given family history in different populations with an application to breast cancer.Semantic proximity Read ↗

Kin-cohort evaluation of relative risks of genetic variants.Semantic proximity Read ↗

Bayesian estimation of a semiparametric recurrent event model with applications to the penetrance estimation of multiple primary cancers in Li-Fraumeni syndrome.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.