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Article

[Association study of the SCN1 gene polymorphism and effective dose of lamotrigine].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova - 1 Jan 2009

Krikova E V, Val'dman E A, Avakian G N, Andreev Ia A, Denisov E V, Rider F K, Biktimerov R R, Chukanova A S, Burd S G

Abstract excerpt

An association between a polymorphism of the SCN1 gene, a therapeutical target of lamotrigine, and an effective dose (a blood plasma concentration) of the drug in patients with epilepsy has been studied. Fifty patients with different forms of epilepsy have been genotyped for the SCN1 IVS5N+5 G>A...

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PMID: 20037572

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20037572-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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