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Article

The function and regulation of TBX22 in avian frontonasal morphogenesis.

Developmental dynamics : an official publication of the American Association of Anatomists - 1 Feb 2010

Higashihori Norihisa, Buchtová Marcela, Richman Joy M

Abstract excerpt

The frontonasal mass gives rise to the facial midline and fuses with the maxillary prominence to form the upper lip. Here we focus on the regulation and function of TBX22, a repressor dynamically expressed in the frontonasal mass. Both FGF and Noggin (a BMP antagonist) strongly induce gTBX22, however, each has opposite effects on morphogenesis - Noggin inhibits whereas FGF stimulates growth. To determine whether...

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Source

Identifiers

PMID: 20033915
DOI: 10.1002/dvdy.22182

Genes

TBX22
DLX5
MSX2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The function and regulation of TBX22 in avian frontonasal morphogenesis.PMID 20033915Read ↗

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