Article
Hepatitis B virus genotype B has an earlier emergence of lamivudine resistance than genotype C.
Antiviral therapy - 1 Jan 2009
Hsieh Ting-Hui, Tseng Tai-Chung, Liu Chun-Jen, Lai Ming-Yang, Chen Pei-Jer, Hsieh Hsin-Ling, Chen Ding-Shinn, Kao Jia-Horng
Abstract excerpt
BACKGROUND: Hepatitis B virus (HBV) genotype B and C seem not to affect the therapeutic response to lamivudine (3TC). Whether a given genotype has an earlier emergence of 3TC resistance remains unclear. We thus conducted this study to elucidate the association of HBV genotype with the emergence of 3TC-resistant strains in Taiwanese patients. METHODS: Forty chronic hepatitis B patients who developed resistance...
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