Hepatitis B virus genotype B has an earlier emergence of lamivudine resistance than genotype C.

doi:10.3851/IMP1454

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Article

Hepatitis B virus genotype B has an earlier emergence of lamivudine resistance than genotype C.

Antiviral therapy - 1 Jan 2009

Hsieh Ting-Hui, Tseng Tai-Chung, Liu Chun-Jen, Lai Ming-Yang, Chen Pei-Jer, Hsieh Hsin-Ling, Chen Ding-Shinn, Kao Jia-Horng

Abstract excerpt

BACKGROUND: Hepatitis B virus (HBV) genotype B and C seem not to affect the therapeutic response to lamivudine (3TC). Whether a given genotype has an earlier emergence of 3TC resistance remains unclear. We thus conducted this study to elucidate the association of HBV genotype with the emergence of 3TC-resistant strains in Taiwanese patients. METHODS: Forty chronic hepatitis B patients who developed resistance...

Topics

Adult
Anti-HIV Agents
DNA, Viral
Drug Resistance, Viral
Female
Genotype
Hepatitis B virus
Hepatitis B, Chronic
Humans
Lamivudine
Male
Multivariate Analysis
Reverse Transcriptase Inhibitors
Taiwan
Time Factors

Source

Open in PubMed

Identifiers

PMID: 20032545
DOI: 10.3851/IMP1454

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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