Article
Prediction of functional impairment and remission in rheumatoid arthritis patients by biochemical variables and genetic polymorphisms.
Rheumatology (Oxford, England) - 1 Mar 2010
Balsa Alejandro, Del Amo Jokin, Blanco Francisco, Caliz Rafael, Silva Lucía, Sanmarti Raimon, Martínez Francisco G, Tejedor Diego, Artieda Marta, Pascual-Salcedo Dora, Oreiro Natividad, Collado Maria D, Andreu Jose L, Graell Eduard, Simón Laureano, Martínez Antonio, Mulero Juan
Abstract excerpt
OBJECTIVE: To develop a model to predict RA outcome based on biochemical variables and single nucleotide polymorphisms (SNPs). METHODS: We collected baseline data from RA patients. SNP genotyping was performed using an oligonucleotide microarray. Remission and severe disability were investigated as outcomes of the study. Logistic regression models and receiver operating characteristic (ROC) curves were used to...
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