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Article

The relation of genetic and environmental factors to systemic inflammatory biomarker concentrations.

Circulation. Cardiovascular genetics - 1 Jun 2009

Schnabel Renate B, Lunetta Kathryn L, Larson Martin G, Dupuis Josée, Lipinska Izabella, Rong Jian, Chen Ming-Huei, Zhao Zhenming, Yamamoto Jennifer F, Meigs James B, Nicaud Viviane, Perret Claire, Zeller Tanja, Blankenberg Stefan, Tiret Laurence, Keaney John F, Vasan Ramachandran S, Benjamin Emelia J

Abstract excerpt

BACKGROUND: Environmental and genetic correlates of inflammatory marker variability are incompletely understood. In the family-based Framingham Heart Study, we investigated heritability and candidate gene associations of systemic inflammatory biomarkers. METHODS AND RESULTS: In offspring participants (n=3710), we examined 11 inflammatory biomarkers (CD40 ligand, C-reactive protein, intercellular adhesion...

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PMID: 20031590
DOI: 10.1161/CIRCGENETICS.108.804245
PMCID: PMC2897047

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