Article
Common genetic variants on chromosome 9p21 confers risk of ischemic stroke: a large-scale genetic association study.
Circulation. Cardiovascular genetics - 1 Apr 2009
Smith J Gustav, Melander Olle, Lövkvist Håkan, Hedblad Bo, Engström Gunnar, Nilsson Peter, Carlson Joyce, Berglund Göran, Norrving Bo, Lindgren Arne
Abstract excerpt
BACKGROUND: Epidemiological studies indicate a genetic contribution to ischemic stroke risk, but specific genetic variants remain unknown, with the exception of a few rare variants. Recent genome-wide association studies identified and replicated common genetic variants on chromosome 9p21 to confer risk of coronary heart disease. We examined whether these variants are associated with ischemic stroke. METHODS AND...
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