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Article

Polymorphisms in COL4A3 and COL4A4 genes associated with keratoconus.

Molecular vision - 20 Dec 2009

Stabuc-Silih Mirna, Ravnik-Glavac Metka, Glavac Damjan, Hawlina Marko, Strazisar Mojca

Abstract excerpt

PURPOSE: Alterations in collagen type IV, alpha-3 (COL4A3) and collagen type IV, alpha-4 (COL4A4) genes may be responsible for a decrease in collagen types I and III, a feature often detected in keratoconus (KC). To evaluate the significance of alterations in COL4A3 and COL4A4 genes in KC patients, we screened both genes and estimated the significance of polymorphisms in Slovenian patients with KC. METHODS: The...

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Identifiers

PMID: 20029656
PMCID: PMC2796875

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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