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Article

Validation of rs2956540:G>C and rs3735520:G>A association with keratoconus in a population of European descent.

European journal of human genetics : EJHG - 1 Nov 2015

Dudakova Lubica, Palos Michalis, Jirsova Katerina, Stranecky Viktor, Krepelova Anna, Hysi Pirro G, Liskova Petra

Abstract excerpt

Corneal ectasias, among which keratoconus (KC) is the single most common entity, are one of the most frequent reasons for corneal grafting in developed countries and a threatening complication of laser in situ keratomileusis. Genome-wide association studies have previously found lysyl oxidase (LOX) and hepatocyte growth factor (HGF) associated with susceptibility to KC development. The aim of our study was to...

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Identifiers

PMID: 25735481
DOI: 10.1038/ejhg.2015.28
PMCID: PMC4613460

Genes

HGF
LOX

Provenance

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