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Article

Keratoconus is not associated with mutations in COL8A1 and COL8A2.

Cornea - 1 Sept 2007

Aldave Anthony J, Bourla Nirit, Yellore Vivek S, Rayner Sylvia A, Khan M Ali, Salem Andrew K, Sonmez Baris

Abstract excerpt

PURPOSE: To evaluate the suggested role of the COL8A1 and COL8A2 genes in the pathogenesis of the corneal ectatic disorders keratoconus and keratoglobus through mutation screening in affected patients. METHODS: DNA extraction, polymerase chain reaction amplification, and sequencing of COL8A1 and COL8A2 were performed in 50 unrelated keratoconus and 2 unrelated keratoglobus patients. RESULTS: No sequence...

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PMID: 17721297
DOI: 10.1097/ICO.0b013e31811dfaf7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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