Article
Absence of significant genetic alterations in the VSX1, SOD1, TIMP3, and LOX genes in Brazilian patients with Keratoconus.
Ophthalmic genetics - 1 Feb 2022
Lopes Alessandro Garcia, de Almeida Gildásio Castello, Miola Marcos Paulo, Teixeira Ronan Marques, Pires Francielly Camilla Bazilio Laurindo, Miani Rodolfo Andrade, de Mattos Luiz Carlos, Brandão Cinara Cássia, Castiglioni Lilian
Abstract excerpt
PURPOSE: To identify inherited or acquired mutations in the VSX1, SOD1, TIMP3 and LOX genes from the combined analysis of corneal and blood samples from patients with Keratoconus. METHODS: The casuistry was consisted of samples of peripheral blood and corneal epithelium from 35 unrelated patients with Keratoconus who were submitted to corneal crosslink treatment. Also, blood and corneal epithelium samples from 89...
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