Article
X-chromosome Forkhead Box P3 polymorphisms associate with atopy in girls in three Dutch birth cohorts.
Allergy - 1 Jul 2010
Bottema R W B, Kerkhof M, Reijmerink N E, Koppelman G H, Thijs C, Stelma F F, Smit H A, Brunekreef B, van Schayck C P, Postma D S
Abstract excerpt
BACKGROUND: The Forkhead Box P3 (FOXP3) gene, located on the X-chromosome, encodes a transcription factor that directs T cells toward a regulatory phenotype. Regulatory T cells may suppress development of atopy. We evaluated whether single-nucleotide polymorphisms (SNPs) of FOXP3 are associated w...
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