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Article

Multipotentiality, homing properties, and pyramidal neurogenesis of CNS-derived LeX(ssea-1)+/CXCR4+ stem cells.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Nov 2005

Corti Stefania, Locatelli Federica, Papadimitriou Dimitra, Donadoni Chiara, Del Bo Roberto, Fortunato Francesco, Strazzer Sandra, Salani Sabrina, Bresolin Nereo, Comi Giacomo P

Abstract excerpt

Achieving efficient distribution of neural stem cells throughout the central nervous system (CNS) and robust generation of specific neurons is a major challenge for the development of cell-mediated therapy for neurodegenerative diseases. We isolated a primitive neural stem cell subset, double positive for LeX(Le) and CXCR4(CX) antigens that possesses CNS homing potential and extensive neuronal repopulating...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16150803
DOI: 10.1096/fj.05-4170fje

Genes

CXCR4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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