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Article

Promoter variant in the catalase gene is associated with vitiligo in Chinese people.

The Journal of investigative dermatology - 1 Nov 2010

Liu Ling, Li Chunying, Gao Jian, Li Kai, Zhang Rui, Wang Gang, Li Chenxin, Gao Tianwen

Abstract excerpt

Vitiligo is an acquired depigmentation disorder, and reactive oxygen species have an important role in the physiology of cell damage. Reduced catalase enzyme activity and accumulation of excessive hydrogen peroxide have been observed in vitiligo. In a hospital-based case-control study of vitiligo...

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Source

Identifiers

PMID: 20613769
DOI: 10.1038/jid.2010.192

Genes

CAT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-20613769-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

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Promoter variant in the catalase gene is associated with vitiligo in Chinese people.PMID 20613769Read ↗

No association between catalase (CAT) gene polymorphisms and susceptibility to vitiligo in a Turkish population.Semantic proximity Read ↗

Evaluation of CAT Variants A-89T, C389T, and C419T in Patients with Vitiligo in the Saudi Population.Semantic proximity Read ↗

Lack of association between the 389C>T polymorphism (rs769217) in the catalase (CAT) gene and the risk of vitiligo: an update by meta-analysis.Semantic proximity Read ↗

The polymorphism of catalase T/C codon 389 in exon 9 and vitiligo susceptibility: a meta-analysis.Semantic proximity Read ↗

Association of the 389 C/T polymorphism of the catalase gene with susceptibility to vitiligo: a meta-analysis.Semantic proximity Read ↗

The catalase gene promoter and 5'-untranslated region variants lead to altered gene expression and enzyme activity in vitiligo.Semantic proximity Read ↗

Lack of association between catalase gene polymorphism (T/C exon 9) and susceptibility to vitiligo in a Turkish population.Semantic proximity Read ↗

Vitiligo susceptibility and catalase gene polymorphisms in Sicilian population.Semantic proximity Read ↗

Association study between catalase gene polymorphisms and the susceptibility to vitiligo in Korean population.Semantic proximity Read ↗

Genetic association of the catalase gene (CAT) with vitiligo susceptibility.Semantic proximity Read ↗

Analysis of allelic variants in the catalase gene in patients with the skin depigmenting disorder vitiligo.Semantic proximity Read ↗

Analysis of oxidative stress status, catalase and catechol-O-methyltransferase polymorphisms in Egyptian vitiligo patients.Semantic proximity Read ↗

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