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Article

Shuttle cloning and nucleotide sequences of Helicobacter pylori genes responsible for urease activity

1 Mar 1991

Abstract excerpt

Production of a potent urease has been described as a trait common to all Helicobacter pylori so far isolated from humans with gastritis as well as peptic ulceration. The detection of urease activity from genes cloned from H. pylori was made possible by use of a shuttle cosmid vector, allowing replication and movement of cloned DNA sequences in either Escherichia coli or Campylobacter jejuni. With this approach,...

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Identifiers

PMID: 2001995
DOI: 10.1128/jb.173.6.1920-1931.1991

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