Article
Association of interleukin-18 gene polymorphisms with calcium oxalate kidney stone disease.
Scandinavian journal of urology and nephrology - 1 Feb 2010
Lai Kuang-Chi, Lin Wei-Yong, Man Kee-Ming, Tsai Chou-Haung, Chen Huey-Yi, Tsai Fuu-Jen, Chen Fun-Jou, Chen Hsin-Yi, Liu Hsin-Ping, Ho Tsung-Jung, Huang Po-Hsun, Liu Po-Len, Lin Feng-Yen, Shen Jui-Lung, Liu Jung-Tung, Chen Yung-Hsiang, Chen Wen-Chi
Abstract excerpt
OBJECTIVE: The interleukin-18 (IL-18) encoding gene has three common single-nucleotide polymorphisms at -607C/A, -137G/C and +105A/C, which have been reported to be associated with several diseases. The aim of this study is to test whether IL-18 polymorphisms could act as genetic markers for renal stone disease. MATERIAL AND METHODS: A control group of 104 healthy subjects, and 272 patients with recurrent calcium...
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