Article
Association of interleukin-1beta gene and receptor antagonist polymorphisms with calcium oxalate urolithiasis.
Journal of endourology - 1 Dec 2007
Mittal Rama D, Bid Hemant K, Manchanda Parmeet K, Kapoor Rakesh
Abstract excerpt
BACKGROUND AND PURPOSE: Genetic polymorphisms of the interleukin-1beta (IL-1beta) promoter region (-511) and exon 5 +3954 and a variable number of tandem repeats in the IL receptor antagonist (IL-1RA) gene have been proposed as markers for calcium oxalate urolithiasis. Because the prevalence of these polymorphisms could be influenced by racial variation/ethnicity, we explored the association of IL-1 gene-cluster...
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