Article
Genetic variation of the human urinary tract innate immune response and asymptomatic bacteriuria in women.
PloS one - 15 Dec 2009
Hawn Thomas R, Scholes Delia, Wang Hongwei, Li Sue S, Stapleton Ann E, Janer Marta, Aderem Alan, Stamm Walter E, Zhao Lue Ping, Hooton Thomas M
Abstract excerpt
BACKGROUND: Although several studies suggest that genetic factors are associated with human UTI susceptibility, the role of DNA variation in regulating early in vivo urine inflammatory responses has not been fully examined. We examined whether candidate gene polymorphisms were associated with altered urine inflammatory profiles in asymptomatic women with or without bacteriuria. METHODOLOGY: We conducted a...
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