Article
Genetic polymorphisms associated with urinary tract infection in children and adults: a systematic review and meta-analysis.
American journal of obstetrics and gynecology - 1 Jun 2024
Yu Jiakun, Varella Pereira Glaucia Miranda, Allen-Brady Kristina, Cuffolo Romana, Siddharth Aditi, Koch Marianne, Chua John W F, Sorrentino Felice, Dytko Oskar, Ng Kaa-Yung, Violette Philippe, Khullar Vik, Wang Zhan Tao, Cartwright Rufus
Abstract excerpt
INTRODUCTION: The lifetime risk of urinary tract infection is known from first-degree relative studies to be highly heritable. Associations have also been observed across the life course from pediatric urinary tract infection to recurrent urinary tract infection in adulthood, suggesting lifelong susceptibility factors. Candidate gene studies and genome-wide association studies have tested for genetic associations...
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