Article
Association of Toll-like receptor 4 gene polymorphism and expression with urinary tract infection types in adults.
PloS one - 3 Dec 2010
Yin Xiaolin, Hou Tianwen, Liu Ying, Chen Jing, Yao Zhiyan, Ma Cuiqing, Yang Lijuan, Wei Lin
Abstract excerpt
BACKGROUND: Innate immunity of which Toll-like receptor (TLR) 4 and CXCR1 are key elements plays a central role in the development of urinary tract infection (UTI). Although the relation between the genetics of TLR4 and CXCR1 and UTI is investigated partly, the polymorphisms and expression of TLR4 and CXCR1 in different types of UTI in adults are not extremely clear. METHODOLOGY/PRINCIPAL FINDINGS: This study...
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