Article
Stainless steel ions stimulate increased thrombospondin-1-dependent TGF-beta activation by vascular smooth muscle cells: implications for in-stent restenosis.
Journal of vascular research - 1 Jan 2010
Pallero Manuel A, Talbert Roden Melissa, Chen Yiu-Fai, Anderson Peter G, Lemons Jack, Brott Brigitta C, Murphy-Ullrich Joanne E
Abstract excerpt
BACKGROUND/AIMS: Despite advances in stent design, in-stent restenosis (ISR) remains a significant clinical problem. All implant metals exhibit corrosion, which results in release of metal ions. Stainless steel (SS), a metal alloy widely used in stents, releases ions to the vessel wall and induce...
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