Article
Versatile modes of peptide recognition by the ClpX N domain mediate alternative adaptor-binding specificities in different bacterial species.
Protein science : a publication of the Protein Society - 1 Feb 2010
Chowdhury Tahmeena, Chien Peter, Ebrahim Shamsah, Sauer Robert T, Baker Tania A
Abstract excerpt
ClpXP, an AAA+ protease, plays key roles in protein-quality control and many regulatory processes in bacteria. The N-terminal domain of the ClpX component of ClpXP is involved in recognition of many protein substrates, either directly or by binding the SspB adaptor protein, which delivers specific classes of substrates for degradation. Despite very limited sequence homology between the E. coli and C. crescentus...
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