Article
Two-dimensional, sex-specific autosomal linkage scan of the number of sodium pump sites.
Journal of hypertension - 1 Apr 2010
Hasstedt Sandra J, Xin Yuanpei, Hopkins Paul N, Hunt Steven C
Abstract excerpt
OBJECTIVES: The sodium pump consists of the membrane-bound enzyme sodium/potassium-ATPase, which exchanges internal sodium ions for external potassium ions. Obesity, hypertension, and diabetes associate with the activity of the sodium pump, motivating gene discovery for sodium pump number. METHODS: Variance components linkage analysis was applied to the number of red blood cell sodium pump sites measured by...
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