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Article

Resistance development profiling of piperacillin in combination with the novel {beta}-lactamase inhibitor BLI-489.

The Journal of antimicrobial chemotherapy - 1 Feb 2010

Ruzin Alexey, Petersen Peter J, Jones C Hal

Abstract excerpt

OBJECTIVES: To evaluate development of resistance to the piperacillin/BLI-489 combination. METHODS: BLI-489 was used at a constant concentration of 4 mg/L. Spontaneous mutation frequency was measured on piperacillin/BLI-489-containing agar plates. Five beta-lactamase-producing strains were expose...

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Identifiers

PMID: 20008048
DOI: 10.1093/jac/dkp435

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20008048-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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