Article
Ovarian cancer tumor infiltrating T-regulatory (T(reg)) cells are associated with a metastatic phenotype.
Gynecologic oncology - 1 Mar 2010
Barnett Jason C, Bean Sarah M, Whitaker Regina S, Kondoh Eiji, Baba Tsukasa, Fujii Shingo, Marks Jeffrey R, Dressman Holly K, Murphy Susan K, Berchuck Andrew
Abstract excerpt
OBJECTIVE: The objective of this study was to examine the clinicopathologic correlates of T-regulatory (T(reg)) cell infiltration in serous ovarian cancers and to define gene signatures associated with high T(reg)s. METHODS: Tumor infiltrating T(reg) and cytotoxic T-cells (CTLs) were quantitated...
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