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Article

Does mtDNA nucleoid organization impact aging?

Experimental gerontology - 1 Aug 2010

Bogenhagen Daniel F

Abstract excerpt

Somatic cells in tissue culture package several copies of mitochondrial DNA (mtDNA) in aggregates known as nucleoids that appear to be remarkably stable. The clustering of multiple mtDNA genomes in a single nucleoid complex may promote the progressive age-related accumulation of deletion and poin...

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Identifiers

PMID: 20004238
DOI: 10.1016/j.exger.2009.12.002
PMCID: PMC2879461

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20004238-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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