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Immunosenescence and age-related viral diseases

30 Apr 2013

Abstract excerpt

Immunosenescence is described as a decline in the normal functioning of the immune system associated with physiologic ageing. Immunosenescence contributes to reduced efficacy to vaccination and increased susceptibility to infectious diseases in the elderly. Extensive studies of laboratory animal models of ageing or donor lymphocyte analysis have identified changes in immunity caused by the ageing process. Most of...

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PMID: 23633071
DOI: 10.1007/s11427-013-4478-0

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