Article
Insights on the structure of amyloid fibrils from site-directed mutagenesis.
Protein and peptide letters - 1 Jan 2009
Corrêa Daniel Henrique do Amaral, Ramos Carlos Henrique Inácio
Abstract excerpt
To test the hypothesis that the ability to form ordered beta-rich amyloid fibers with identical structures is a generic property of proteins we present a study on the overall structures of fibers formed by apomyoglobin mutants that either stabilize or destabilize the native state or the intermediate. Our results indicate that, at least at the macroscopic level, ordered beta-rich amyloid fibers have similar...
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