Article
Fibrillogenesis of apomyoglobin facilitated by aggregation sequence of yeast Sup35 in various regions.
FEBS letters - 28 Feb 2005
He Yingbo, Tang Huadong, Yi Zhiwei, Zhou Hao, Luo Yongzhang
Abstract excerpt
To examine the effect of aggregation sequence QGGYQQQYNP from yeast Sup35 on fibril formation of sperm whale apomyoglobin (apoMb), we constructed several mutants via substitution. Urea-induced unfolding of apoMb confirms that the substitution of the aggregation sequence does not significantly affect the stability of the mutants compared to wild type (WT) at pH 4.2. Under this condition, however, despite the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
