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Article

Three-dimensional culture alters primary cardiac cell phenotype.

Tissue engineering. Part A - 1 Feb 2010

Akins Robert E, Rockwood Danielle, Robinson Karyn G, Sandusky Daniel, Rabolt John, Pizarro Christian

Abstract excerpt

The directed formation of complex three-dimensional (3D) tissue architecture is a fundamental goal in tissue engineering and regenerative medicine. The growth of cells in 3D structures is expected to influence cellular phenotype and function, especially relative cell distribution, expression profiles, and responsiveness to exogenous signals; however, relatively few studies have been carried out to examine the...

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Identifiers

PMID: 20001738
DOI: 10.1089/ten.tea.2009.0458
PMCID: PMC2813151

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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