Article
Multidrug resistance protein 3 R652G may reduce susceptibility to idiopathic infant cholestasis.
World journal of gastroenterology - 14 Dec 2009
Chen Xiu-Qi, Wang Lin-Lin, Shan Qing-Wen, Tang Qing, Lian Shu-Jun
Abstract excerpt
AIM: To evaluate the role of genetic factors in the pathogenesis of idiopathic infant cholestasis. METHODS: We performed a case-control study, including 78 infants with idiopathic infant cholestasis and 113 healthy infants as controls. Genomic DNA was extracted from peripheral venous blood leukocytes using phenol chloroform methodology. Polymerase chain reaction was used to amplify the multidrug resistance...
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