Article
Neuregulin-1 and the P300 waveform--a preliminary association study using a psychosis endophenotype.
Schizophrenia research - 1 Aug 2008
Bramon Elvira, Dempster Emma, Frangou Sophia, Shaikh Madiha, Walshe Muriel, Filbey Francesca M, McDonald Colm, Sham Pak, Collier David A, Murray Robin
Abstract excerpt
OBJECTIVE: Neuregulin-1 (NRG1) has been put forward as a susceptibility gene for schizophrenia. We investigated the association between Neuregulin-1 and the P300 wave, a schizophrenia endophenotype. METHODS: Participants were 64 patients with DSM-IV schizophrenia or schizoaffective disorder, 97 of their non psychotic relatives and 35 unrelated controls. The P300 wave was extracted from the electroencephalogram...
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