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High expression of UBE2T predicts poor prognosis and survival in multiple myeloma

7 Jan 2019

Abstract excerpt

Multiple myeloma (MM) is one of hematological malignancies, characterized by malignant proliferation of plasma cells. Biomarkers play an important role in evaluating the development and prognosis of MM. Ubiquitin-conjugating enzyme E2T (UBE2T) is served to connect with particular E3 ubiquitin ligase to degraded-related substrates, contributing to DNA repair in the Fanconi anemia pathway. Also, numerous evidences...

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PMID: 30622320
DOI: 10.1038/s41417-018-0070-x

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