Article
Mononuclear phagocytes: a major population of effector cells responsible for rejection of allografted tumor cells in mice.
Proceedings of the National Academy of Sciences of the United States of America - 15 Feb 1991
Yoshida R, Takikawa O, Oku T, Habara-Ohkubo A
Abstract excerpt
To understand the in situ mechanism of immunological response of recipient animals to allografted tumor cells, the types of cells that infiltrated into the rejection site were examined. When Meth A cells (H-2d) were given i.p. to an allogeneic [C57BL/6 (H-2b)] strain of mouse, the tumor cells ceased to grow on the 6th day, accompanied by an i.p. infiltration of leukocytes. The tumor cells were totally eliminated...
Topics
- Animals
- Antibodies, Monoclonal
- Cytotoxicity, Immunologic
- Flow Cytometry
- Graft Rejection
- H-2 Antigens
- Mice
- Mice, Inbred C57BL
- Mice, Inbred Strains
- Neoplasm Transplantation