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Article

L-serine synthesis in the central nervous system: a review on serine deficiency disorders.

Molecular genetics and metabolism - 1 Mar 2010

Tabatabaie L, Klomp L W, Berger R, de Koning T J

Abstract excerpt

The de novo synthesis of the amino acid L-serine plays an essential role in the development and functioning of the central nervous system (CNS). L-serine displays many metabolic functions during different developmental stages; among its functions providing precursors for amino acids, protein synthesis, nucleotide synthesis, neurotransmitter synthesis and L-serine derived lipids. Patients with congenital defects...

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Source

Identifiers

PMID: 19963421
DOI: 10.1016/j.ymgme.2009.10.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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