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Article

The role of periodontal ligament cells in delayed tooth eruption in patients with cleidocranial dysostosis.

Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie - 1 Nov 2009

Lossdörfer Stefan, Abou Jamra Bassel, Rath-Deschner Birgit, Götz Werner, Abou Jamra Rami, Braumann Bert, Jäger Andreas

Abstract excerpt

OBJECTIVE: The clinical appearance of patients with cleidocranial dysplasia (CCD), which is caused by mutations in the RUNX2 gene, is characterized by anomalies of the clavicles, thorax, spine, pelvis and extremities and by disturbances of the skull and tooth development. Of orthodontic relevance are multiple supernumerary teeth associated with delayed tooth eruption. The present investigation is based on the...

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Share to Cell Differentiation
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19960292
DOI: 10.1007/s00056-009-9934-x

Genes

RUNX2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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