Article
Delayed tooth eruption and suppressed osteoclast number in the eruption pathway of heterozygous Runx2/Cbfa1 knockout mice.
Archives of oral biology - 1 Jun 2004
Yoda Shuichi, Suda Naoto, Kitahara Yutaka, Komori Toshihisa, Ohyama Kimie
Abstract excerpt
Genetic studies have recently identified a mutation of one allele of runt-related gene 2 (RUNX2/CBFA1) as the cause for an autosomal-dominant skeletal disorder, cleidocranial dysplasia (CCD), which is characterised by hypoplasia of the clavicles and calvariae and widened sutures and fontanelles....
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