Article
Effect of progerin on the accumulation of oxidized proteins in fibroblasts from Hutchinson Gilford progeria patients.
Mechanisms of ageing and development - 1 Jan 2010
Viteri Gabriela, Chung Youn Wook, Stadtman Earl R
Abstract excerpt
The mutation responsible for Hutchinson Gilford Progeria Syndrome (HGPS) causes abnormal nuclear morphology. Previous studies show that free radicals and reactive oxygen species play major roles in the etiology and/or progression of neurodegenerative diseases and aging. This study compares oxidat...
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